Annual Reports on NMR Spectroscopy 65

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.* Provides updat. Read more... Content: Front Cover; Annual Reports on NMR Spectroscopy; Copyright Page; Contents; Contributors; Preface; Chapter 1: NMR of Antimicrobial Peptides; 1. Introduction; 2. Mechanism of Action; 5. Solvent Considerations; 6. Structures of Antimicrobial Peptides in Micelles; 7. Organic Membrane Mimetic Solvents; 8. Orientation in Detergent Micelles; 9. Structure Determination of Larger Complexes; 10. Endotoxin Binding by Antimicrobial Peptides; 12. Solid-State NMR of Antimicrobial Peptides; 13. Peptide Orientation in Bilayers; 17. Conclusions; Acknowledgments Chapter 2: NMR Studies of Protein Folding: Folding Studies of Calcium-Binding Lysozyme and alpha-Lactalbumin1. Introduction; 2. Hydrogen-Deuterium Exchange; 3. Structure and Dynamics of Unfolded States of Proteins; 4. Hydrogen Exchange Pulse Labelling and Real-Time NMR; 5. Concluding Remarks; References; Chapter 3: Applications of the NOE in Molecular Biology; 1. Introduction; 3. Faster and Better; 4. Complexes; 5. Interactions with Water; 6. NOEs Involving Nuclei Other than 1H; Abbreviations; Acknowledgment; References; Chapter 4: Recent Applications of REDOR to Biological Problems 1. Introduction5. Conclusions and Summary of Earlier Applications; References; Chapter 5: Electrophoretic NMR-Ions, Molecules, Mixtures, Pores and Complexes; 1. Theoretical and Historical Perspectives; References; Chapter 6: Two-Dimensional Magnetic Resonance Spectroscopy on Biopsy and In Vivo; 1. Introduction; 3. Spectral Filtering; 8. Human Muscle; 9. Human Bone Marrow; 11. Brain; 13. 2D Spectral Fitting (ProFit); Abbreviations; References; Subject Index Abstract: Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy.* Provides updat